Measurement of Amniotic Fluid Erythropoietin (EPO) Concentration in Abnormal Pregnancy and the Its Correlation with Umbilical Vein Serum EPO Levels
- VernacularTitle:异常妊娠羊水中促红细胞生成素的测定及其与脐血中促红细胞生成素相关性研究
- Author:
Yajun XIA
;
Tao SHANG
;
Juan DU
- Publication Type:Journal Article
- Keywords:
Pregnancy complications;
Hypertension;
Diabetes mellitus;
Erythropoietin;
Fetal anoxia
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure the concentration of the amniotic fluid EPO(AFEPO) and investigate the relationship between AFEPO levels and fetal hypoxia. Methods Their AFEPO and the umbilical vein serum EPO (UVSEPO) were measured thirty pregnancy induced hypertension pregnancies (PIH group) , 30 gestational diabetic pregnancies (Diabetic group) and 25 normal pregnancies (control group) were terminated by cesarean section by using a chemiluminescent enzyme labeled immunometric assay (CELIMA). Meantime, umbilical artery pH (UapH), base excess(UaBE) and UapO2 and so on were also measured. Results The mean concentrations of AFEPO and UVSEPO in PIH (1.42?0.33 and 1.63?0.37) and Diabetic group (1.53?0.25 and 1.81? 0.34) were significantly higher than those in control group (0.91?0.11 and 1.13?0.14), ( P
