Study on Screening Vitamin K Deficiency in Neonate and Intant by Testing Acarboxyprothrombin
- VernacularTitle:应用凝血酶原前体蛋白筛查住院新生儿及小婴儿维生素K缺乏及其对策研究
- Author:
Yuee SUN
;
Yuzhi QIN
;
Zheng YANG
- Publication Type:Journal Article
- Keywords:
Infcent, newborn;
Prothrombin;
protein precursors;
Neonatal screening;
Vitamin K deficiency
- From:
Chinese Journal of Perinatal Medicine
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Screen out incidence of vitamin K deficiecy and complicated with hemorrhage in newborn patients, infant patients and normal neonates, and also study on the treatment of vitamin K deficiency. Methods Using emzymoimmunoelectrophoresis to test PIVKA Ⅱ in umbilical and vein blood. Results The incidence of vitamin K deficiency in normal neonates, newborn patients (≤ 5 days) and infants patients (25~60 days) are 31.2%,47.6% and 31.8%. The incidence of hemorrhage in newborn patients (≤5 days) is 26.0%, infant patients (25~60 days) is 66.6%. Intramuscular injection of vitamin K 1 1 mg is the proper dosage to prevent and treat vitamin K deficiency. Conclusion The neonates right after birth or about 25 days after birth, especially those of breast feeding and who are getting lievr and gall diseases should receive vitamin K 1 to prevent vitamin K deficiency.
