Studies on the expression of fibronectin and integrins in epiretinal membranes
- VernacularTitle:纤维连接蛋白及其整合素受体在视网膜前膜中的表达
- Author:
Qiu WANG
;
Guiyun WANG
;
Xiaoguang ZHANG
- Publication Type:Journal Article
- Keywords:
Vitreoretinopathy,proliferative/physiopathology;
Fibronectins;
Antigens,CD 29;
Immunohistochemistry
- From:
Chinese Journal of Ocular Fundus Diseases
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of the fibronectin (FN) and ? 1 integrin (? 1) in epiretinal membranes(ERM) of eyes with proliferative vitreoretinopathy(PVR). Methods Twenty epiretinal membranes were obtained from eyes undergone vitrectomy for retinal detachment complicated with PVR and observed by immunohistochemical methods. Results Overexpression of FN and ? 1 were observed in 18 and 16 membranes respectively. Conclusion The synergism of FN and ? 1 in their action mignt be one of the important roles in the development of PVR.
