Effect of Frequent Small Hematometachysis on Blood Rheology in Patients with Hepatocirrhosis Accompanied by Hemorrhage of Upper Digestive Tract and Its Therapeutic Evaluation
- VernacularTitle:少量多次输血对肝硬化并上消化道出血患者血液流变学的影响及临床疗效评价
- Author:
Xiangwen SHAO
;
Qinghua ZHANG
;
Xiuqin WANG
- Publication Type:Journal Article
- Keywords:
Hepatocirrhosis;
Hemorrhage of upper digestive tract;
Blood rheology;
Blood transfusion
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Object The purpose of this study was to analyze the changes in blood rheology in paitents with hepatocirrhosis accompanied by hemorrhage of upper digestive tract,explore the effect of frequent small bllod transfusion on it,after controlled hemorrhage and its clinical singnificance.Methods Thirty-four patients with hepatocirrhosis accompanied by hemorrhage of upper digestive tract were recruited into this study,10 days after controlled hemorrhage.These patients all underwent blood transfusion(200ml fresh blood or 2-unit concentrated erythrocyte) every month.Blood rheology data were obtained before and after 3 times blood transfusion,regular observed the liver function and further hemorrhage time interval.Results There were significantly elevation of whole blood specific viscosity(SV),blood plasma SV,fibrinogen,and hematocrit after treament,The frequent small blood transfusion led to reduce significantly in erythrocyte sedimentation,ALT,AST,TBiL,and significantly prolonged hemorrhage time interval further.Conclusions Frenquent small blood transfusion to patients with hepatocirrhosis could change the blood reology,remission illness state,prolongating the time interval of hemorrhage next occured.
