Preoperative Thyroid-stimulating Hormone Levels as a Predictor of Thyroid Carcinoma.
10.16956/kjes.2010.10.4.220
- Author:
Sung Yup JOUNG
1
;
Hoon Yub KIM
;
Woo Sang RYU
;
Sang Uk WOO
;
Gil Soo SON
;
Jae Bok LEE
;
Jeoung Won BAE
Author Information
1. Department of Surgery, Korea University College of Medicine, Seoul, Korea. endocrsurg@gmail.com
- Publication Type:Original Article
- Keywords:
Thyroid carcinoma;
Thyroid stimulating hormone;
Differentiated thyroid cancer
- MeSH:
Humans;
Lymph Nodes;
Neoplasm Metastasis;
Retrospective Studies;
Thyroid Gland*;
Thyroid Neoplasms*;
Thyroid Nodule;
Thyrotropin*
- From:Korean Journal of Endocrine Surgery
2010;10(4):220-223
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study investigated the effects of serum thyroid-stimulating hormone (TSH) levels in predicting malignancy-associated differentiated thyroid cancer (DTC) and benign thyroid nodules. METHODS: Between January 2005 and December 2007, 346 patients underwent thyroid surgery at one hospital. Their records were retrospectively reviewed. RESULTS: Sixty-nine percent (237 of 346) of the patients had DTC. The mean preoperative TSH level was higher than in the malignant group (5 uIU/ml vs 0.4 uIU/ml). The rate of malignancy was the 71% in patients with TSH levels >5 uIU/ml. The TSH level of DTC with metastasis of the lymph node was higher than that with non-metastasis (3.08 uIU/ml vs 2.09 uIU/ml, P<0.01) CONCLUSION: The likelihood of DTC increases with higher serum TSH concentration. Serum TSH level might be useful in predicting malignant nodular thyroid lesion.
