A study on patterns and lower limit's measurement of cerebral blood flow autoregulation of hypertensive rats
- VernacularTitle:高血压动脉硬化脑血流自动调节类型及其下限测定的实验研究
- Author:
Qingchun GAO
;
Ruxun HUANG
;
Jinsheng ZENG
;
Zhenpei SU
;
Yingxian CHEN
;
Jianwe CHEN
- Publication Type:Journal Article
- Keywords:
Brain;
Blood flow velocity;
Blood pressure;
Ultrasonography
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of hypertensive arteriosclerosis on cerebral blood flow autoregulation (CBFA), and to introduce a new method to measure the lower limit. METHODS: The blood velocities and blood pressure was recorded simultaneously and the curves of CBFA were analyzed and classified into classical and non-classical pattern. The lower limit were determined by clinical closing pressure (CCP) and the curve CBFA. RESULTS: When the blood pressure was decreasing, the classical and non-classical pattern of the cerebral blood flow autoregulation were 25% and 75% respectively in normal SD rats, while they were 40.55% and 54.45% respectively in renovascular hypertensive rats (RHR). However, when the blood pressure was elevating, the classical and non-classical pattern were 76.47% and 23.53% respectively in SD rats, while they were all classical in RHR. Furthermore, in SD and RHR ras, the lower limits measured by CCP were well in accordance with that measured by CBFA. CONCLUSION: Hypertensive arteriosclerosis could influence the limits and the patterns of cerebral blood flow autoregulation. The lower limit of CBFA can be measured and analyzed by CCP.
