Percentage change on natural killer subsets of peripheral blood and decidua in between normal early pregnancy and spontaneous abortion
- VernacularTitle:自然流产中外周血和蜕膜组织自然杀伤细胞亚群的比例变化
- Author:
Qian HOU
;
Yaoying ZENG
;
Zinen WANG
- Publication Type:Journal Article
- Keywords:
Decidua;
Killer cells, natural;
Abortion;
EstrogJPens;
Progesterone
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To determinate the percentage change on natural killer(NK) subsets of peripheral blood and decidua in between normal early pregnancy and spontaneous abortion. METHODS: Flow cytometry was used to detect the expression of CD56 and CD16 on lymphocytes of decidua and peripheral blood in normal early pregnancy and spontaneous abortion. RESULTS: In peripheral blood, the percentage of CD56 + of spontaneous abortion tended to decrease in comparison with normal early pregnancy, and the percentage of CD56 +CD16 + in spontaneous abortion was significantly less than that in normal early pregnancy. The percentages of different natural killer subsets in decidua of spontaneous abortion were significantly lower than those in decidua of normal early pregnancy. CONCLUSION: The decrease of CD56 +NK cells in decidua may be one of causes for abortion, the loss of CD56 + and CD56 +CD16 +NK cells in peripheral blood could have a diagnostic value for spontaneous abortion.
