Effect of nitric oxide on proteinuria excretion in rats suffering from renal ischemia-reperfusion
- VernacularTitle:肾缺血再灌注大鼠蛋白尿的生成及NO的作用
- Author:
Xinliang WANG
;
Shansheng HUANG
;
Xiaoling CHEN
;
Dianhua WANG
;
Yiling LING
- Publication Type:Journal Article
- Keywords:
Kidney failure, acute;
Reperfusion injury;
Nitric oxide;
Proteinuria
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the urinary protein (UP) excretion in rats suffering from renal ischemia-reperfusion (I-R) and effect of nitric oxide on it. METHODS: SD rats were used to establish the renal I-R model. Sodium nitroprusside (SNP), N ?-nitro-L-arginine (L-NNA) and aminoguanidine (AG) were used to determine the effect of nitric oxide on UP excretion under renal I-R. Quantitative analysis of UP was made by chromatometry. UP species were separated by SDS-PAGE. RESULTS: Renal I-R caused significant increase in UP ( P
