Caveolae-caveolin and associated signaling molecules
- VernacularTitle:细胞质膜微囊-微囊蛋白及其相关信号分子
- Author:
Kang YAO
;
Biao XU
- Publication Type:Journal Article
- Keywords:
Receptor;
Cytoplasm;
Cell membrane;
Signal transduction;
Signal peptides
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Caveolae, specialized vesicular invaginations of the plasma membrane ,have attracted increasing attentions to those who are studing siginal transduction .Many proteins involved in signal transduction have been found enriched in these microdomains.Caveolins,as marker proteins of caveolae,form a scaffold onto which many classes of signaling molecules can assemble at steady state or after ligand-induced activiton .In addition to concentrating these signal transducers within a distinct region of the plasma membrane ,caveolin binding may functionally regulate the activation state of caveolae-associated signaling molecules.Thus,an emerging notion is that caveolae are signaling processing centers which orchestrate signaling events at the cell surface that influence cell function .
