Advances in the mechanism of herpes simplex virus-I type thymidine kinase gene therapy of tumor
- VernacularTitle:单纯疱疹病毒I型胸苷激酶基因治疗肿瘤机制研究进展
- Author:
Xiangliang HE
- Publication Type:Journal Article
- Keywords:
Gene therapy;
Neoplasms;
Thymidine kinase
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
Herpes simplex virus-I type thymidine kinase gene is a drug sensitivity gene. It is still not very clear about how it kills tumor cells, the article reviewed in short in a few aspects such as molecular structure of TK gene, TK enzyme,bystander effect,gap junction intercellular communication,cell apoptosis and phagocytosis,inflammation and immunity reaction, and the developing direction of TK gene.
