Influence of Corticosteroid on Peripheral Blood Lymphocyte in Secondary Syphilis and Prognosis of Syphilis
- VernacularTitle:皮质类固醇对二期显性梅毒外周血T淋巴细胞及其预后的影响
- Author:
Pingyu ZHOU
;
Kanghuang LIAO
;
Ming XU
- Publication Type:Journal Article
- Keywords:
Syphilis;
Glucocorticoids;
T－lymphocytes;
Prognosis
- From:
Chinese Journal of Dermatology
1994;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate if corticosteroid could influence periphe ral blood CD3＋、 CD4＋ and CD8＋ cells in secondary syphilis and the prognosis of syphilis. Methods CD3＋、 CD4＋、 CD8＋ cells were detected in 11 patients wh o took corticosteroid and 20 patients who did not. The effects on the therapeuti c effect of lesions were observed. Results The levels of CD3＋ and CD4＋ in peri pheral blood were significantly lower in corticosteroid group than those in cont rols. The proportion of patients whose RPR test turned to negative and lesions c ured was significantly lower in corticosteroid group than those in controls with in the first three months after treatment. Conclusion Corticosteroid administrat ion decreases the levels of CD3＋ and CD4＋ in secondary syphilis and therefore influence the prognosis of syphilis.
