Influence of preoperatively intraarterial infusion chemotherapy on the expression of p16 and Rb protein in human colon cancer
- VernacularTitle:术前区域动脉灌注化学治疗对人结直肠癌细胞p16蛋白与Rb蛋白表达的影响及其临床意义
- Author:
Jin GU
;
Xinxin LU
;
Pei LI
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Chemotherapy;
Protein p16;
Retinoblastoma
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of preoperative regional chemotherpy on colon cancer cell cycle.Methods30 colorectal cancer patients received intraarterial chemotherapy 10 days before the radical resection.The expression of p16 and Rb protein was examined by immunohistochemistry.Result was compared with the control group.Results Labeling index (LI) of p16 protein was (35?19)% in treatment group, while in control group L1 was (16?8)%,( P
