The expression and clinical significance of vascular endothelial growth factor in primary hepatocellular carcinoma
- VernacularTitle:血管内皮生长因子在原发性肝细胞癌中的表达及其作用
- Author:
Tianbao ZHOU
;
Mouxin SHEN
;
Huaqun FU
;
Aiguo YANG
- Publication Type:Journal Article
- Keywords:
LIVER NEOPLASMS/pathol;
CARCINOMA,HEPATOCELLULAR/pathol;
NEOPLASMS METASTASIS;
LIVER NEOPLASMS/blood supply;
VESCULAR ENDOTHELIAL GROWTH FACTOR
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the expression of vascular endothelial growth factor (VEGF) and invasion, metastasis of primary hepatocellular carcinoma (PHCC). Methods Paraffin-embedded specimens from 30 patients with PHCC undergoing radical resection were studied. Agiogenesis was assessed by the expression of VEGF and microvascular density (MVD) using LSAB immunohistochemical staining. Results (1) The level of VEGF and MVD in PHCC was higher than that in the paratumorous tissue (P5*!cm) and small ones (diameter ≤5*!cm). (4) The expression of VEGF was positively correlated with MVD (P
