Urinary trypsinogen activation peptide assay for the early prediction of severe acute pancreatitis
- VernacularTitle:尿中胰蛋白酶原激活肽对重症急性胰腺炎的早期预测价值
- Author:
Congqing JIANG
;
Zhongli AI
;
Zhisu LIU
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Trypsinogen
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of TAP in the early prediction of severe acute pancreatitis (SAP) and to compare it with acute physiology and chronic health evalutionⅡ (APACHEⅡ).Methods We observed the association between TAP concentration and the severity of acute pancreatitis with competitive enzyme-linked immunosorbent assay(ELISA). Urine samples were collected for the measurement of TAP concentration at admission, 24,48,and 72*!h after from 41 patients with acute pancreatitis (AP) (12 severe cases, and 29 mild) who presented within 48*!h of the onset of symptoms and from 11 control patients, while APACHEⅡ scores were recorded at 48*!h after admission. Results The TAP at admission of SAP (95*!nmol/L) was signficantly higher than that of mild (20*!nmol/L; P
