Correlation of p53 and vascular endothelial growth factor expression to angiogenesis in gastric carcinoma and its clinical significance
- VernacularTitle:胃癌组织中p53和血管内皮生长因子的表达与血管生成的关系及其意义
- Author:
Xuezhi MING
;
Haoran YIN
;
Zhenggang ZHU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Genes, p53;
Endothelial growth factors;
Neovascularization, pathologic
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the expression of p53 and vascular endothelial growth factor (VEGF) to angiogenesis in gastric carcinoma. Methods The expression of p53、VEGF and microvascular density (MVD) in gastric carcinoma was examined by immunohistochemical staining in 60 cases.Results There was a close correlation between MVD, p53 as well as VEGF expression and several clinicopathological factors including tumor size(P
