Plastic Changes of Motor Network after Constraint-Induced Movement Therapy.
10.3349/ymj.2004.45.2.241
- Author:
Yun Hee KIM
1
;
Ji Won PARK
;
Myoung Hwan KO
;
Sung Ho JANG
;
Peter K W LEE
Author Information
1. Department of Physical Medicine and Rehabilitation, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea. yunkim@smc.samsung.co.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Constraint-induced movement therapy;
functional MRI;
motor network;
plasticity
- MeSH:
Adult;
Cerebrovascular Accident/physiopathology/*rehabilitation/*therapy;
Human;
Middle Aged;
Motor Cortex/*physiology;
Movement;
*Neuronal Plasticity;
*Physical Therapy Techniques;
Support, Non-U.S. Gov't
- From:Yonsei Medical Journal
2004;45(2):241-246
- CountryRepublic of Korea
- Language:English
-
Abstract:
The effects of short-term constraint-induced movement (CIM) therapy on the activation of the motor network were investigated with functional magnetic resonance imaging (fMRI). Movement of the less-affected arms of five patients was restricted and intensive training of the affected upper limb was performed. Functional MRI was acquired before and after two-weeks of CIM therapy. All patients showed significant improvement of motor function in their paretic limbs after CIM therapy. For three patients, new activation in the contralateral motor/premotor cortices was observed after CIM therapy. Increased activation of the ipsilateral motor cortex and SMA was observed in the other patient. Our results demonstrated that plastic changes of the motor network occurred as a neural basis of the improvement subsequent to CIM therapy following brain injury.
