C-myc gene amplification, p16 gene alterations and HBV-DNA integration in hepatocellular carcinoma
- VernacularTitle:C-myc基因扩增、p16基因变异和乙型肝炎病毒DNA整合与肝细胞癌的相关性研究
- Author:
Fabo QIU
;
Peilin WANG
;
Liqun WU
- Publication Type:Journal Article
- Keywords:
Carcinoma, hepatocellular;
Oncogenes
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
005,?=2), but they were significantly higher than that of PB(0%, 0/12) as well as liver cirrhosis (LC) tissues (8%, 1/12) in LC group (12 cases), respectively (2)A total of 3 homozygous deletions and no point mutations of exon 1 and 2 in p16 gene in HCC were found (3)The discrepancies of the positive rates of HBV- DNA integration among normal liver (14%, 2/14), LC(67%, 8/12) and HCC (97%, 28/29) were statistically significant (?2=29434*!5, P
