Suppressive effect of combination of t-PA,heparin and homoharringtonine on formation of PVR aftervetreoretinal surgery
- VernacularTitle:组织型纤溶酶原激活剂、肝素和高三尖杉酯碱对术后增生性玻璃体视网膜病变的抑制作用
- Author:
Yan MEI
;
Tianguo YUAN
;
Jie WANG
- Publication Type:Journal Article
- Keywords:
Vitreoretinopathy,proliferative/dru in group therapy;
Harringtonines/therapeutic use;
Homoharringtonine/therapeutic use;
Heparin/therapeutic use
- From:
Chinese Journal of Ocular Fundus Diseases
1996;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the suppressive effect of combination of tissue plasminogen activator(t-PA),heparin and homoharringtonine on the formation of proliferative vitreoretinopathy (PVR) after vitreoretinal surgery. Methods Forty-three cases (44 eyes)of complicated retinal detachment who receivedvitreoretinal surgery were divided into 2 groups.Twenty cases(20 eyes)in group A were treated by intravitreal injection of above mentioned drugs at the end of operation,while no intraocular injection of drugs given in 23cases(24 eyes)in group B.The mean follow-up period was 7.9 months. Result The rate of recurrent PVR in group A was 15.8%(3 of 19),and 45.5%(10 of 22) in group B (P
