The relationship between nitric oxide and gastric mucosal injury induced by reserpine in rats
- VernacularTitle:一氧化氮与利血平致大鼠胃粘膜损伤的关系
- Author:
Gaofeng MA
;
Jieping YU
;
Lihua TIAN
;
Liqian RU
- Publication Type:Journal Article
- Keywords:
Nitric oxide;
Reserpine;
Gastric mucosa;
Injuries
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the relationship between nitric oxide (NO) and gastric mucosal injury induced by reserpine in rats. METHODS: Sixteen healthy male Wistar rats were randomly divided into control group and experimental group (n=8). NO contents and malondialdehyde(MDA) contents in plasma, gastric mucosa of the rats were respectively determined with Cadmium-reduct plus Greiss and TBA; nitric oxide synthase in gastric walls of the rats were observed using NADPH-diaphorase histochemistry and quantitatively measured with image analyzer.RESULTS: The NO contents in both plasma and gastric mucosa of experimental group were significantly lower than that in control group (P
