Molecular biological responses to severe posttraumatic stress
- VernacularTitle:严重创伤后应激反应的调控机理
- Author:
Duhu LIU
;
Yongping SU
;
Tianmin CHENG
- Publication Type:Journal Article
- Keywords:
Stress disorders, post-traumatic;
Hypothalamo-hypophyseal system;
Sympathetic nervous system;
Transcription factors
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Traumatic stress in the normal individual results in activation of the sympatho-adrenal system causing a rise in noradrenaline and adrenaline, acute phase response in liver ,and activation of the hypothalamic-pituitary-adrenocortical(HPA)system resulting in elevated levels of cortisol. Studies in animals and in humans with posttraumatic stress disorder indicate that successful adaptation to stress is a prerequisite for the survival of all organisms living in an enviroment in which noxious stimuli are constantly present.
