Study on Analgesic,Anti-inflammatory and Anti-thrombotic Effects of Rhizoma Cynanchi Stauntonii
- VernacularTitle:白前的镇痛、抗炎和抗血栓形成作用
- Author:
Yaqin SHEN
;
Mingfa ZHANG
- Publication Type:Journal Article
- Keywords:
Rhizoma Cynanchi Stauntonii;
analgesics;
anti-inflammatory agents;
anti-thrombotics4
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the analgesic,anti-inflammatory and anti-thrombotic effects of Rhizoma Cynanchi Stauntonii.METHODS:Experiments were carried out on conventional mouse models of inflammation and pain,and on a thrombotic model of using direct current continuously to stimulate the carotid artery on one side of the neck of anesthetic rat.RESULTS:Alcoholic extract of Rhizoma Cynanchi Stauntonii,in dosages of 5g herb/kg and 15g herb/kg ig,prolonged the latent period of tail flip response to hot water stimulation and reduced acetic acid-induced writhing frequency,and inhibited xylene-induced swelling of the ear and carrageenin-induced swelling of the planta.The extract,10g herb/kg ig,prolonged in vivo coagulative time and thrombotic time induced by electric stimulating artery in rats.CONCLUSION:Rhizoma Cynanchi Stauntonii has analgesic,anti-inflammatory and anti-thrombotic effects.
