Immunohistochemical study of C5 complement in experimental early myocardial ischemia
- VernacularTitle:实验性早期心肌缺血补体C5的免疫组织化学研究
- Author:
Bingjie HU
;
Yuchuan CHEN
;
Jiazhen ZHU
- Publication Type:Journal Article
- Keywords:
Early myocardial infarction Complement Immunohistochemistry
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Experimental acute myocardial ischemia model of rat was established, and the changes of C5 complement in the ischemic myocardia were studied with immunohistochemistry and image analysis technique. The results showed that the positive reaction of C5 could be observed in ischemic myocardia at 15 min after ischemia, and the positive reaction area increased along with the prolongation of the ischemic period. It is concluded that the positive reaction of C5 in cardiomyocytes is a quite sensitive marker of early myocardial ischaemia.The immunohistochemical detection of C5 in cardiomyocytes will be a meaningful tool for the postmortem diagnosis of early myocardial ischaemia.
