An immunohistochemical study of the fibronectin in experimental viral myocarditis
- VernacularTitle:实验性病毒性心肌炎纤维连接蛋白的免疫组化研究
- Author:
Jianding CHENG
;
Yuchuan CHEN
;
Bingjie HU
- Publication Type:Journal Article
- Keywords:
Viral myocarditis Fibronectin Forensic pathology Immunohistochemistry
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
For the purpose of establishment of a diagnostic method of mild viral myocarditis,an experimental mild viral myocarditis model was induced in Balb/c murine by coxsackie virus B 3.The cardiac tissue secfion were stained by LSAB-immunohistochemical method with anti fibronectin(Fn) antibody. The results demonstrated that the Fn deposition was found in the myocardium of mice with myocarditis and the mild degeneration of cardiomyocytes could be identified by Fn LSAB immunohistochemical staining.It is suggested that the Fn deposition in the myocardium tissue is one of the reliable marks of myocardium inflammation.
