Solid phase microextraction for both fenfluramine and amphetamine stimulants
- VernacularTitle:芬氟拉明和苯丙胺类兴奋剂的固相微萃取
- Author:
Junting LIU
;
Rubo LI
;
Feng TAN
- Publication Type:Journal Article
- Keywords:
Solid phase microextraction Solid phase extraction Fenfluramine Stimulant
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The present paper reports that the fenfluramine(FA), amphetamine(AP) and methamphetamine(MA) were extracted from the blood by the solid phase microextraction(SPME). The drugs were extracted for 15 min under the condition of 70℃ by a polydimethylsiloxane fiber. d5-methamphetamine(IS) was used as an internal standard. GC/MS was used for analysis with the injection method of derivatization on column. The ions at m/z 268(FA), m/z 240(AP), m/z 254(MA) and m/z 258(IS) in the selected ion minitoring chromatograms were selected for quantitation. Each compound was detectable at least 0 01～0 03 ?g/g. By determination of fenfluramine in poisoning blood, it is proved that this method would be demonstrated to be simple and accurate.
