Study on the postmortem stabiliity of fibronectin for the diagnosis of myocardial infarction
- VernacularTitle:纤维连接蛋白诊断心肌梗死的死后稳定性研究
- Author:
Bingjie HU
;
Yuchuan CHEN
;
Jiazhen ZHU
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Fibronectin;
Immunohistochemistry;
Postmortem stability
- From:
Chinese Journal of Forensic Medicine
2000;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Experimental acute myocardial ischemia model of dog was established, and the postmortem stability of fibronectin for the diagnosis of mycardial infarction was studied with immunohistochemistry and image analysis technique. The results showed that the positive reaction areas of fibronectin in ischemic myocardial tissues decreased along with the prolongation of postmortem interval, but positive reaction of fibronectin could still be found in ischemic myocardia kept for 4 weeks postmortem. No positive reaction for fibronectin could be found in normal myocardia when kept for different times. So fibronectin is a quite stable marker for the postmortem diagnosis of myocardial infarction, and is of practical value in the forensic practice.
