Assay of Correlative Oncogene of Testicular Tissues in Cryptorchids
- VernacularTitle:隐睾组织P53,Rb,nm23,C-berB-2基因研究
- Author:
Guoqing LIU
;
Lixuan WANG
;
Wei ZHENG
- Publication Type:Journal Article
- Keywords:
Cryptorchidism;
Testicular neoplasms;
Gene
- From:
Journal of Chinese Physician
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
The P53,Rb,nm23,C-berB-2 genes of testicular tissues were assayed with immunohistochemical method in 30 hereditary cryptorchids.The results indicate that nm23 of 4 cases and C-berB-2 of 2 cases were positively stained in 30 cases,and one of the 6 cases was both positively stained in an abdominal undescended testis.The findings suggest that aberrantion of nm23,C-berB-2 genes is associated with testicular neoplasms of retained testis,specifically abdominal undescended testis has trend to variation of correlative oncogenes of testicular tissues.
