Effects of permissive hypercapnia on systemic and regional oxygen metabolism in sheep with acute respiratory distress syndrome
- VernacularTitle:允许性高碳酸血症对急性呼吸窘迫综合征绵羊全身和肠道氧代谢的影响
- Author:
Haibo QIU
;
Yan TAN
;
Shaoxia ZHOU
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome;
Hypercapnia;
Hemodynamics;
Oxygen;
Metabolism
- From:
Chinese Journal of Anesthesiology
1997;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of permissive hypercapnia (PHC)on cardiovascular system, oxygen metabolism and gastrointestinal function with acute respiratory distress syndrome(ARDS). Methods In 18 sheep with LPS induced ARDS, hemodynamics, oxygen metabolism and gastrointestinal intramucosal pH(pHi)were observed at different tidal volume(V T).Results PHC was induced by decreasing V T from 16 ml/kg to 4 7ml/kg.Compared with those at V T 16 ml/kg, cardiac index decreased significantly in PHC (P
