The Relationship of Expression of CD_(44)V_6, PCNA to Lymph Node Metastasis in Colorectal Carcinoma
- VernacularTitle:大肠癌中CD_(44)V_6、PCNA表达与淋巴结转移的关系
- Author:
Hua ZHAO
;
Dazuo FENG
;
Sanlin LEI
- Publication Type:Journal Article
- Keywords:
Colorectal tumor,Malignancy;
Immunohistochemical technique;
Lymph node metastasis
- From:
Journal of Chinese Physician
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
To explore the relationship of expression of metastasis associated protein-CD 44 V 6 and proliferating cell nuclear antigen(PCNA) to lymph node metastasis in colorectal carcinoma,randomly selected patients with colorectal carcinoma who underwent coloproctectomy plus D 2～D 3 lymph node dissection were studied.The 104 patients were divided into:A group (n=48) without lymph node metastasis and B group(n=56) with metastasis.The expressions of CD 44 V 6 and PCNA were assayed by immunohistochemical technique.The results indicated that the 56 cases(75%) of B group were positive for expressions of CD 44 V 6 and PCNA,there was obvious correlation between both the expressions and lymph node metastasis(P
