Experimental Study of Inhibiting Effect of Interferon-alpha 1b on Proliferation of Human Tenon Capsule Fibroblasts
- VernacularTitle:干扰素?-1b对人眼Tenon囊成纤维细胞增殖抑制的实验研究
- Author:
Chulong HUANG
;
Yuqing LAN
;
Zhikuan YANG
;
Mingkai LIN
- Publication Type:Journal Article
- Keywords:
Interferon_?-1b;
fibroblast;
MTT method
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To observe the inhibiting effect of Interferon-alpha 1b(IFNa-1b) on proliferation of human tenon capsule fibroblasts. METHODS: Human tenon capsule fibroblasts were cultured in vitro and MTT method was used to detect the inhibiting effect of IFNa-1b on human tenon capsule fibroblasts. RESULTS: There was significant difference in OD values between 10~6IU/ml group(0. 1 109?0. 0 585) and control group(0.2535?0. 0502), the inhibition rate in IFN group was 56.25%. CONCLUSION: IFNa-1b has significant effect on inhibiting proliferation of human tenon capsule fibroblasts.
