Changes of plasma calcitonin gene-related peptide and endothelin concentrations during induction anesthesia and intubation following propofol administration
- VernacularTitle:异丙酚诱导插管对血浆降钙素基因相关肽及内皮素水平的影响
- Author:
Xiaoju JIN
;
He ZHANG
;
Zhaofang LIU
- Publication Type:Journal Article
- Keywords:
Propofol;
Intubation,intratracheal;
Calcitonin gene-related peptides;
Endothelins
- From:
Chinese Journal of Anesthesiology
1995;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of plasma calcitonin gene-related peptide (CGRP) and endothelin (ET) during propofol-induced anesthesia and intubationMethods Thirty-six patients were randomly allocated to receiving intravenous administration with propofol 2mg/kg ( group PP, n=20) or sodium thiopental group (SP, n=16) The venous bloos samples were taken to measure the plasma CGRP and endothelin (ET) concentrations, together with systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR), immediately before induction, 2min after P or SP administration, 2min, 7min, 15min after intubationResults SBP decreased immediately after induction in both groups (P005), increased markedly in group SP (P
