Effects of different analgesic methods on neuroendocrine and cytokines
- VernacularTitle:术后不同镇痛方法对神经内分泌和细胞因子的影响
- Author:
Shaoyang CHEN
;
Yingmin ZHANG
;
Liang LIANG
- Publication Type:Journal Article
- Keywords:
Pain,postoperative;
Analgesia,patient-controlled;
Stress;
Injections,epidural;
Injections,intravenous
- From:
Chinese Journal of Anesthesiology
1996;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influences of different analgesic methods on blood sugar, stress hormones and cytokinesMethods According to different postoperative analgesic methods, 30 patients immediately after elective cholecystectomy, were randomly divided into four groups: normal saline was infused epidurally in group C as control; analgesia via epidural infusion of morphine 2 mg in group EM; patient-controlled analgesia via epidural or intravenous fentanyl in group PCEFA or group PCIFABlood sugar, cortisol, insulin, interlukin-2 (IL-2), interlukin-6 (IL-6) and tumor necrosis factor-?(TNF-?) levels were determined during the perioperative periodResults Postoperative visual analog score was higher in group C than that in group EM, group PCEFA or group PCIFA (P005)Conclusions Postoperative application of PCEFA can much more help to maintain the stability of neuroimmunoendocrinal system
