Therapeutic effects of inhaled nitric oxide in patients with pulmonary hypertension after mitral valve replacement
- VernacularTitle:吸入一氧化氮治疗二尖瓣狭窄术后肺动脉高压的研究
- Author:
Hui JIANG
;
Renfu ZHANG
;
Zhaohui MA
- Publication Type:Journal Article
- Keywords:
Nitric oxide;
Mitral valve stenosis;
Postoperative complications;
Hypertension,pulmonary
- From:
Chinese Journal of Anesthesiology
1996;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
2 67kPa) after MVR were enrolled in the study Parameters in hemodynamics and oxygenation were measured with Swan Ganz technique , 5min before NO inhalation (T 1), 5,15 and 30min following NO 20ppm inhalation (T 2,T 3,T 4), 15min after stopping NO 20ppm inhalation (T 5), 15min and 5h following NO 6ppm inhalation (T 6,T 7) and 15min before and after weaning from mechanical ventilator (T 8,T 9) respectively Results Compared with those at T 1, at T 2 pulmonary artery pressure, pulmonary vascular resistance, alveolar arterial oxygen difference and intrapulmonary shunting significantly decreased, but arterial oxygen partial pressure, oxygen content and oxygen availability index increased significantly (P0 05) Conclusions The persistently inhaled low dose NO is effective and safe for the pulmonary hypertension induced with heart surgery
