Study of platelet aggregations in patients with coronary heart disease and the effect of ticlopidine treatment
- VernacularTitle:冠心病患者血小板聚集功能及噻氯匹啶作用的观察
- Author:
Yujie LI
;
Weiyi MAI
;
Qunying ZENG
;
Qing HE
;
Lili LIU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Platelet aggregation inhibitors;
Ticlopidine;
Adenosine diphosphate
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the platelet aggregations in patients with coronary heart disease(CHD) and the effect of ticlopidine treatment. METHODS: Platelet aggregations induced by adenosine diphosphate(ADP), epinephrine(EPI), collagen(Coll), arachidonic acid(ACA) in CHD group before and after ticlopidine treatment were measured by turbidity assay. RESULTS: Maximum ratios of platelet aggregations (max%) induced by ADP,EPI in CHD group (0.78?0.23,0.86?0.25) were significantly higher than that of control group (0.65?0.19,0.73?0.21, P
