Changes of metallothionein contents in plasma and tissues of rabbit with atherosclerosis
- VernacularTitle:动脉粥样硬化家兔血浆及组织金属硫蛋白含量变化
- Author:
Shulian LI
;
Xiaohong WANG
;
Lin XUE
;
Jing LIN
;
Chunyu ZHAO
;
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Metallothionein;
Atherosclerosis;
Lipoproteins, LDL;
Malondialdehyde
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the level of metallothionein (MT) in liver, aorta and plasma of rabbit with atherosclerosis (AS) in order to recognize the alteration of oxidative defense system in body when AS occurred.METHODS:Preparation of AS model of rabbit induced by having high-fat diet for eight weeks; the levels of MT and malondialdehyde (MDA) were measured in the tissues of liver and aorta and plasma of rabbit.RESULTS:The MT levels in liver tissues and plasma in atherosclerotic group increased 318%( P
