Effects of propofol on glomerular and renal tubular functions
- VernacularTitle:异丙酚对肾小球和肾小管功能的影响
- Author:
Heling ZHAO
;
Wei CHEN
;
Xichun ZHU
- Publication Type:Journal Article
- Keywords:
Propofol;
Enflurane;
Kidney glomerulus;
Kidney tubules
- From:
Chinese Journal of Anesthesiology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of propofol on glomerular and renal tubular functionsMethods Twenty-five patients without renal disease were randomly assigned to two groups: propofol group(n=13) and enflurane group(n=12), The creatinine, urea nitrogen, uric acid(UA) , ? 2 -microglobulin( ? 2-MG) concentrations in serum and urine were measured before induction of anesthesia, and 1, 2, 3, and 24h after induction Albumin(ALb), immunoglobulin G(IgG), pH, and protein in urine were also examinedResults In both groups , the urine concentrations of ? 2-MG , ALb and IgG were significantly increased following the administrations compared with those before induction of anesthesia (P
