Estimating 24-Hour Urine Sodium Level with Spot Urine Sodium and Creatinine.
10.3346/jkms.2014.29.S2.S97
- Author:
Ho Seok KOO
1
;
Yong Chul KIM
;
Shin Young AHN
;
Se Won OH
;
Suhnggwon KIM
;
Ho Jun CHIN
;
Jung Hwan PARK
Author Information
1. Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
24-hr Urine Sodium;
Spot Urine Sodium;
Spot Urine Creatinine
- MeSH:
Adult;
Aged;
Algorithms;
Area Under Curve;
Creatinine/*urine;
Demography;
Female;
Glomerular Filtration Rate;
Humans;
Male;
Middle Aged;
ROC Curve;
Sodium, Dietary/*urine;
Urine Specimen Collection
- From:Journal of Korean Medical Science
2014;29(Suppl 2):S97-S102
- CountryRepublic of Korea
- Language:English
-
Abstract:
The 24-hr urine sodium excretion level was estimated based on the spot urine sodium, and the efficacy of the formula was validated to determine the status of low salt intake <100 mEq Na/day. The 24-hr urine samples were collected from 400 patients. The 24-hr urine creatinine level was estimated with the use of three formulas: a newly derived Korean equation (E24UCR_K), and Tanaka (E24UCR_T) and Cockcroft-Gault (E24UCR_CG) equations. The correlation coefficients between the estimated and measured 24-hr urine creatinine for these three equations were 0.863, 0.846, and 0.896, respectively (All P<0.001). After estimating the 24-hr urine sodium levels, the correlation coefficients between the estimated and measured 24-hr urine sodium levels were 0.466, 0.490, and 0.516, respectively (All P<0.001). The sensitivity of three formulas to estimate the measured 24-hr urine sodium> or =100 mEq/day using the estimated amount> or =100 mEq/day was 84.3%, 87.6%, and 84.8%, respectively. In conclusion, the three equations used to estimate the 24-hr urine sodium content were useful to determine the status of low salt intake.
