Changes of blood cytokines values and inductions of cytokines expressions in patients after cardiac valve replacement with CPB
- VernacularTitle:体外循环术后血中细胞因子及其诱生能力变化的研究
- Author:
Yi HUANG
;
Haibo HUANG
;
Hongjun LAN
- Publication Type:Journal Article
- Keywords:
Cardiopulmonary bypass;
Interleukin 1;
Interleukin 2;
Interleukin 4;
Interleukin 8;
Tumor necrosis factor;
Receprtors,Interleukin 2
- From:
Chinese Journal of Anesthesiology
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the changes of blood cytokines values and inductions of cytokines expressions after CPB and cardiac valve replacement. Methods Thirty patients undergoing cardiac valve replacement were randomly selected, The plasma cytokines levels or activities and inductions of cytokine expressions were measured before CPB, 1st, 3rd, 7th, 14th d after operation.Results Compared with the baselines, IL 1 activity and souluble interleukin 2 receptor(SIL 2R) level increased on the 1st, 3rd d , then decreased significantly on the 7th d, plasma IL 8 level increased in 14 d after CPB, but IL 2 activity decreased during 7 d postoperatively(P0.05); induction of IL 1 expression increased significantly on the 1st d and decreased on the 3rd d (P
