Change of synapsins in hippocampal formation during spacial learning and memory in rats
- VernacularTitle:大鼠海马结构在空间辨别性学习记忆时突触素表达的变化
- Author:
Baogui SU
;
Sanqiang PAN
;
Hui HAN
;
Xiaomei YANG
- Publication Type:Journal Article
- Keywords:
Synapsins;
Learning;
Memory;
Immunohistochemistry;
Rats
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM and METHODS: The immunohistochemical method was used to study the on synapsin ex- press in hippocampal formation during spatial learning and memory in rats. RESULTS: (1 ) In control group there are diffuse brown granules without any obvious granular product in hippocampal fornation and in model group there are synapsin products in the hippocampal formation, especially in the subregion CA3, CA4 and the dentate gyrus after water maze flamed for one week. After two weeks water maze thened the hippocampal formation appear the same dis- tribution of the product edes with darker staining. (2) The light dendity of synapsin products between the model and the control groups showed significant differences, that in the model group was highter than that in the control group (P
