Carbon monoxide, another gaseous messenger of the body
- VernacularTitle:一氧化碳,生物体内又一种重要的气体信使
- Author:
Qiaobing HUANG
;
Kesen ZHAO
- Publication Type:Journal Article
- Keywords:
Carbon monoxid;
Gases;
Signal transduction
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Endogenous carbon monoxide (CO) is proposed to be an intracellular signaling molecule. As a new gaseous messenger, CO shares with nitric oxide (NO) the ability of modulating neuroendocrine function and inducing vasorelaxation, mainly by stimulating soluble guanylate cyclase and regulating the level of cGMP. This review emphasized the endogenous source of CO and the interaction of CO- and NO-generating systems. It also discussed the biological effects of CO and the underlying mechanisms.
