Effects of isoflurane inhalation on the electroencephalogram ,intracranial pressure and hemodynamics during neurosurgery
- VernacularTitle:神经外科手术异氟醚麻醉对脑电图和颅内压及血液动力学影响
- Author:
Ying HE
;
Shuzhen ZHANG
;
Xiaoli ZHOU
- Publication Type:Journal Article
- Keywords:
Anesthesia ,inhalation;
Isoflurane;
Electroencephalogram;
Intracranial pressure;
Hemodynamics
- From:
Chinese Journal of Anesthesiology
1995;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of isoflurane at different concentration on the quantitative electroencephalogram(SEF and BIS) , intracranial pressure(ICP) and hemodynamics during neurosurgery Methods Thirty ASA grade Ⅰ Ⅱ patients with saddle tumor ,scheduled for selective operation, were randomly divided into three groups after induction with fentanyl propofol vecuronium and intubation Anesthesia was maintained with inhalation of 0 5,1 0 or 1 5 MAC of isoflurane in each group respectively MAP,HR,ICP,SEF and BIS were recorded before induction,reaching the designed MAC, at incision ,sawing bones and opening dura Results SEF and BIS decreased significantly with increases in concentration of isoflurane MAP decreased markedly at1 5 MAC compared with that at 0 5 MAC (P
