Effect of lipopolysaccharide on apoptosis of human umbilical vein endothelial cells
- VernacularTitle:脂多糖对人脐静脉内皮细胞凋亡的影响及意义
- Author:
Yong SONG
;
Baoling MAO
;
Jianchun WANG
- Publication Type:Journal Article
- Keywords:
Lipopolysaccharides;
Endothelium, vascular;
Cells;
Lung
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the mechanism of lipopolysaccharide (LPS) on vascular endothelial cell(VEC) damage. METHODS: By using cytometry techniques, we studied the effects of LPS on apoptosis of human umbilical vein endothelial cells (HUVECs) in vitro . RESULTS: LPS was able to induce apoptosis of HUVECs in a time-dose-dependent fashion.CONCLUSION:Apoptosis might play a role in LPS-induced damage of vascular endothelial cells.