The expression and effect of IL-4 in human palatine tonsil
- VernacularTitle:扁桃体组织中白细胞介素-4的表达和意义
- Author:
Tao ZHANG
;
Yong DING
;
Jiqun WANG
;
Zhanquan YANG
;
Zhen DONG
- Publication Type:Journal Article
- Keywords:
Tonsil;
Hypersensitivity;
Interleukin-4
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the allergic disease in recurrent tonsillitis. METHODS: Immunohistochemical technique was used to investigate interleukin-4(IL-4) production in tonsil. RESULTS:The result showed that: a higher incidence of IL-4 producing cells were found in the tonsils of all ages, and a high density of IL-4 was found in the reticular crypt epithelium and extrafollicular, but low density in germinalcenter. IL-4 has been shown play a crucial role in the pathogensis of allergic disease. CONCLUSION:Allergic disease is an important reason of recurrent tonsillitis. The conclusion will give a new way to cure recurrent tonsillitis.