Advances of ubiquitin-conjugating pathway in eukaryotes
- VernacularTitle:真核泛素缀合途径研究进展
- Author:
Jianming CHEN
;
Yingnian YU
- Publication Type:Journal Article
- Keywords:
Ubiquitin;
Biology
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
A Review] A large quantity of intracellular structural and regulatory proteins can be covalently attached to ubiquitin posttranscriptionally and thus modified. The ubiquitination of proteins serves as targeting signals, making ubiquitinated proteins distributed to different parts of the cells, changing the activities, the interaction between macromolecules and the half-life of proteins. Therefore, ubiquitin conjugation is implicated in numerous metabolic processes in eukaryotes. Ubiquitin conjugates its protein substrates via a cascade reaction. This paper is a review of recent advances in this area.
