Effect of thiopentone, midazolam, etomidate and propofol on the serum potassium increase, muscle fasciculations and myalgia following suxamethonium administration
- VernacularTitle:不同麻醉诱导药对血钾浓度变化及肌颤和肌痛的影响
- Author:
Shiying YUAN
;
Shanglong YAO
- Publication Type:Journal Article
- Keywords:
serum potassium;
fasciculation;
myalgia;
Thiopentone;
Midazolam;
Etomidate;
Propofol
- From:
Chinese Journal of Anesthesiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of thiopentone, midazolam, etomidate and propofol on the suxamethonium-induced serum potassium increase, muscle fasciculations and myalgia Methods Sixty patients, ASA class Ⅰ-Ⅱ were allocated randomly to receiving intravenous thiopentone 5mg/kg(thiopentone-group), midazolam 0.3mg/kg( midazolam-group), etomidate 0.3mg/kg(etomidate-group)or propofol 2mg/kg(propofol-group) respectively, followed by intravenous suxamethonium and tracheal intubation. Serum potassium concentration was measured before induction and intubation and after intubation. The incidences of muscle fasciculation during induction and postoperative mylgia were observed .Results As compared with that before induction ,the serum potassium levels in thiopentone- and etomidate-group increased significantly by 3.4% and 5.3% respectively after induction (P0.05).The incidences of muscle fasciculation and postoperative myalgia inmidazolam- and propofol -group were significantly lower than in thiopentone- and etomidate -group (P
