Significance of metallothionein expression in invasive ductal breast cancer
- VernacularTitle:乳腺癌组织中金属硫蛋白表达的意义
- Author:
Ruifen ZHANG
;
Xianmao LUO
;
Hongtu ZHANG
;
Huijuan WEI
- Publication Type:Journal Article
- Keywords:
Metallothionein;
Breast neoplasms;
Prognosis
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To asses the presence and clinical significance of metallothionein,(MT) in primary invasive ductal carcinoma of the breast. METHOD: 96 cases of routinely fixed and paraffin-embedded primary breast carcinomas were investigated with the labelled avidin biotin immunohistochemical method. RESULTS: The positive staining for MT observed was 52.1% (50/96). In most cases both nuclear and cytoplasmic staining was seen. A statistically association was found between MT positive staining and nuclear grade( P