Studying progression in gene p73
- VernacularTitle:p73基因研究进展
- Author:
Yongyi LIU
;
Xueyun ZHONG
- Publication Type:Journal Article
- Keywords:
Genes;
Genes, structural;
Genes, suppressor,tumor
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
p73, a first p53 relative, has recently been identified as a new structural and functional homologue of the transcription factor p53. However, it is unclear whether this protein functions as a tumor suppressor. p73L, a second human p53-related gene, which shows strong amino-acid similarity to p73. In this article, we shall discuss the cloning, location, expression and functions of these two new candidate tumor suppressor genes and look forward to the future study.