The observation on apoptosis from vitrectomy specimens of proliferative vitreoretinopathy
- VernacularTitle:增生性玻璃体视网膜病变玻璃体切割物的细胞凋亡观察
- Author:
Hua YANG
;
Hongbing GUAN
;
Xi ZHANG
- Publication Type:Journal Article
- Keywords:
Vitreoretinopathy,proliferative/pathologyCell death
- From:
Chinese Journal of Ocular Fundus Diseases
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
urpose To investigate apoptosis in vitrectomy specimens of proliferative vitreoretinopathy. Methods Vitrectomy specimens from 60 cases of different classes of proliferative vitreoretinopathy were studied by TdTmediated dUTP nick end labelling(TUNEL)method. Results The characteristic change of apoptosis was observed in all vitrectomy specimens.The amount of apoptotic nonpigmentary cell is gradually decreasing along with the development of proliferative vitreoretinopathy,and apoptotic pigmentary cells are observed. Conclusion There are different kinds of apoptosis cell in vitrectomy specimens of proliferative vitreoretinopathy.It is suggested that apoptosis might be one of the important mechanisms of regulating the degree in proliferative vitreoretinopathy.