Preliminary Study on HL -60 Cellular Wither Induced by Chloroform Extract of Yisuiling
- VernacularTitle:益髓灵氯仿提取物诱导HL—60细胞凋亡的初步研究
- Author:
Xinyi CHEN
;
Debin SHAO
;
Liye ZHAO
- Publication Type:Journal Article
- Keywords:
Yisuiling cell culture cell wither dephagocytosis/drug action magakaryocyte/drug action@Yisuiling chloroform extract
- From:
Journal of Traditional Chinese Medicine
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The experiment was conducted on the actions of 5 kinds of reagents on HL - 60 cellular wither, viz. Yisuiling chloroform extract, rabbit serum chloroform extract, rabbit liver paste chloroform extract, Etoposide, and normal rabbit serum. Results revealed that after fluid incubation for a short period, the HL-60 cultured cells showed no wither in the former 4 groups under microscope and flowing cytometer. Among them, action was strongest in rabbit liver paste of Yisuiling extract group, similar to the positive control of Etoposide. Followed by rabbit serum, and the action was weak in Yisuiling chloroform extract. There was no obvious action of induced wither by normal rabbit serum. The mechanism of induced wither is still under investigation.