Influence of sodium ferulate on MDA, SOD, ET and NO during myocardial ischemia and reperfusion injury
- VernacularTitle:阿魏酸钠对兔心肌缺血再灌注损伤MDA、SOD、ET和NO的影响
- Author:
Youqing LI
;
Jiansong ZHANG
;
Hongwei CAI
- Publication Type:Journal Article
- Keywords:
Sodium ferulate;
Reperfusion injury;
Malondialdehyde;
Superoxide dismutase;
Endothelin;
Nitric oxide
- From:
Chinese Journal of Anesthesiology
1997;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the protective effects of sodium ferulate (SF) on rabbit myocardial ischemia reperfusion injury. Method: Sixteen rabbits were divided randomly into three groups: group A undergoing all procedures except for ischemia-reperfusion and treatment, group B given the routine treatment after ischemia-reperfusion, and group C receiving the routine treatment combined with the intravenous infusion of SF 40mg?kg~(-1) after ischemiareperfusion. Result: Group C showed a significant reduction in myocardial MDA content and plasma ET level (P
