Research on the potential antioxidation of propofol with ESR
- VernacularTitle:异丙酚抗氧化性的ESR研究
- Author:
Yunfei CAO
;
Weifeng YU
;
Mengchao WU
- Publication Type:Journal Article
- Keywords:
Propofol;
Electron spin resonance;
Oxygen free radical
- From:
Chinese Journal of Anesthesiology
1997;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
500?mol/L) of propofol was needed; In biological system near the range of anaesthetic concentration, propofol effectively scavenged oxygen free radical produced by respiratory burst of PMN. Conclusion: Propofol scavenging hydroxyl radical generated in biological and nonbiological system,may be one of the main mechanisms of its antioxidation,the intralipid component of Diprivan may affect its antioxidation.